Molecular Characterization of Chimeric Staphylococcus aureus Strains from Waterfowl.

ABSTRACT: Staphylococcus aureus is a versatile pathogen that does not only occur in humans but also in various wild and domestic animals, including several avian species. When characterizing S. aureus isolates from waterfowl, isolates were identified as atypical CC133 by DNA microarray analysis. They differed from previously sequenced CC133 strains in the presence of the collagen adhesin gene cna; some also showed a different capsule type and a deviant spa type. Thus, they were subjected to whole-genome sequencing. This revealed multiple insertions of large regions of DNA from other S. aureus lineages into a CC133-derived backbone genome. Three distinct strains were identified based on the size and extent of these inserts. One strain comprised two small inserts of

SUBMITTER: Monecke S 

PROVIDER: S-EPMC10821479 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature