The value of intraovarian autologous platelet rich plasma in women with poor ovarian reserve or ovarian insufficiency: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To assess the value of intraovarian PRP in women with low ovarian reserve.

Search strategy

Screening of databases from inception to January 2023 using the keywords related to "Platelet-rich plasma" AND "poor ovarian reserve" OR "ovarian failure".

Selection criteria

Fourteen studies (1632 participants) were included, 10 included women with POR, 1 included women with POI and 3 included both POR and POI women.

Data collection and analysis

Extracted data included study settings, design, sample size, population characteristics, volume, timing and preparation of PRP administration, and outcome parameters.

Main results

AMH level was evaluated in 11 studies (2099 women). The mean difference (MD) was 0.09 with 95% CI of - 0.06, 0.24 (P = 0.25). Antral

SUBMITTER: Maged AM 

PROVIDER: S-EPMC10821562 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature