The association between psoriasis, psoriasis severity, and inflammatory bowel disease: a population-based analysis.

ABSTRACT:

Background

The skin-gut axis, characterized by bidirectional communication between the skin and gut, plays a crucial role in the pathogenesis of psoriasis and inflammatory bowel diseases (IBD).

Objectives

We aimed to explore the association between psoriasis and IBD and identify predictors associated with IBD development among patients with psoriasis.

Design

Retrospective cohort study.

Methods

A retrospective study which utilized an electronic database from the Meuhedet Health Maintenance Organization (MHMO) in Israel. Psoriasis was categorized as severe if any systemic agent or phototherapy was administered. Univariate and multivariate logistic regressions were used to identify specific predictors for IBD, with adjustments made for potential confounders. The s

SUBMITTER: Shani U 

PROVIDER: S-EPMC10822082 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature