Genomic characterization of Bacillus cereus isolated from food poisoning cases revealed the mechanism of toxin production.

ABSTRACT:

Introduction

Bacillus cereus is a ubiquitous opportunistic human pathogen that causes food intoxications worldwide. However, the genomic characteristics and pathogenic mechanisms of B. cereus are still unclear.

Methods

Here, we isolated and purified nine strains of B. cereus (LY01-LY09) that caused vomiting, diarrhea and other symptoms from four foodborne outbreaks happened in Guizhou Province in southwest China from June to September 2021. After colony observation, Gram staining, microscopic examination and biochemical test, they were identified as B. cereus. The genomic characteristics, phylogenetic relationships and virulence factors of the isolated strains were analyzed at the genome level. Genome sequencing, comparative genomic analysi

SUBMITTER: Zhou Q 

PROVIDER: S-EPMC10822677 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature