Visualization of small brain nuclei with a high-spatial resolution, clinically available whole-body PET scanner.

ABSTRACT:

Objective

To verify the visibility of physiological ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) uptake in nuclei in and around the brainstem by a whole-body (WB) silicon photomultiplier positron emission tomography (SiPM-PET) scanner with point-spread function (PSF) reconstruction using various iteration numbers.

Methods

Ten healthy subjects (5 men, 5 women; mean age, 56.0 ± 5.0 years) who underwent ¹⁸F-FDG PET/CT using a WB SiPM-PET scanner and magnetic resonance imaging (MRI) of the brain including a spin-echo three-dimensional sampling perfection with application-optimized contrasts using different flip angle evolutions fluid-attenuated inversion recovery (3D-FLAIR) and a 3D-T1 magnetization-prepared rapid gradient-echo (T1-MPRAGE) images were enroll

SUBMITTER: Shinohara Y 

PROVIDER: S-EPMC10822807 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature