Association between low values of mean arterial pressure and impaired cognitive performance in older patients with mild cognitive impairment: cross-sectional preliminary findings from the STRENGTH Project.

ABSTRACT:

Background

Uncontrolled blood pressure (BP) is a risk factor for Mild Cognitive Impairment (MCI) and dementia.

Aims

This study examined the relationship between BP and clinical/cognitive/neuropsychological aspects in MCI individuals.

Methods

MCI patients underwent clinical, functional, cognitive and metacognitive, as well as psychological assessments. Social network, lifestyle characteristics, and medication prescriptions were also evaluated. Each patient underwent BP measurements.

Results

Lower values of systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were associated with poorer cognitive performance. Notably, MAP showed greater capability in detecting impairments in attention and visuospatial abilities compared to SBP and DBP.

Discu

SUBMITTER: Santillo E 

PROVIDER: S-EPMC10822812 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature