Emergence and spread of SARS-CoV-2 variants of concern in Canada: a retrospective analysis from clinical and wastewater data.

ABSTRACT:

Background

The spread of SARS-CoV-2 has been studied at unprecedented levels worldwide. In jurisdictions where molecular analysis was performed on large scales, the emergence and competition of numerous SARS-CoV-2lineages have been observed in near real-time. Lineage identification, traditionally performed from clinical samples, can also be determined by sampling wastewater from sewersheds serving populations of interest. Variants of concern (VOCs) and SARS-CoV-2 lineages associated with increased transmissibility and/or severity are of particular interest.

Method

Here, we consider clinical and wastewater data sources to assess the emergence and spread of VOCs in Canada retrospectively.

Results

We show that, overall, wastewater-based VOC identification provides simila

SUBMITTER: Champredon D 

PROVIDER: S-EPMC10823614 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature