Efficacy and safety of mesenchymal stem cells in patients with acute ischemic stroke: a meta-analysis.

ABSTRACT:

Objective

This meta-analysis and systematic review were conducted to comprehensively evaluate the efficacy and safety of mesenchymal stem cells in patients with acute ischemic stroke.

Method

We conducted a manual search of electronic databases, including PubMed, Embase, the Cochrane Library, and Web of Science, with a search deadline set for February 1, 2023. Data analysis was performed using Stata version 15.0.

Result

A total of 9 randomized controlled studies were included, involving a total of 316 people, including 159 mesenchymal stem cells and 147 control groups. Results of meta-analysis: Compared to a placebo group, the administration of mesenchymal stem cells resulted in a significant reduction in the National Institutes of Health Stroke Scale (NIHSS) scores am

SUBMITTER: Huang H 

PROVIDER: S-EPMC10823675 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature