The impact of lymphadenectomy on ovarian clear cell carcinoma: a systematic review and meta-analysis.

ABSTRACT:

Background

Ovarian clear cell carcinoma (OCCC) shares treatment strategies with epithelial ovarian cancer (EOC). Due to OCCC's rarity, there's a lack of prospective studies on its surgery, resulting in heterogeneous and limited existing data. This study aims to clarify the prognostic significance of lymphadenectomy in OCCC patients.

Methods

We systematically searched Web of Science, Scopus, PubMed, and Google Scholar until July 2023 for studies investigating lymphadenectomy's effects on OCCC patients. We calculated pooled hazard ratios (HR) with 95% confidence intervals (CI). This study is registered in PROSPERO (CRD42021270460).

Results

Among 444 screened articles, seven studies (2883 women) met inclusion criteria. Our analysis revealed that lymphadenectomy significa

SUBMITTER: Liu Y 

PROVIDER: S-EPMC10823682 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature