Temporal Changes in Clinical Characteristics and Outcomes of Adults With Congenital Heart Disease.

ABSTRACT:

Background

The purpose of this study was to assess differences in the clinical characteristics (defined by congenital heart disease [CHD] anatomic and physiologic classification scheme) of adults with CHD across different eras, and how these differences influence outcomes (heart failure hospitalization and all-cause mortality).

Method

Patients were divided into depending on year of baseline encounter: cohort #1 (1991-2000, n = 1,984 [27%]), cohort #2 (2001-2010, n = 2,448 [34%]), and cohort #3 (2011-2020, n = 2,847 [39%]). Patients were classified into 3 anatomic groups (simple, moderate, and complex CHD) and 4 physiologic stages (stage A-D).

Results

There was a temporal increase in the proportion of patients in physiologic stage C (17% vs 21% vs 24%, P < .001), and s

SUBMITTER: Egbe AC 

PROVIDER: S-EPMC10823874 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature