Drug therapies for obstructive sleep apnoea: a systematic review and meta-analysis protocol.

ABSTRACT:

Introduction

Obstructive sleep apnoea (OSA) is a common disorder that can affect the quality of life and increase the risk for psychiatric, neurological and cardiometabolic diseases. Despite the significant burden, it poses on health and well-being, there is a lack of evidence regarding the use of drug therapies in these patients. This work aims to evaluate the efficacy and safety of pharmacological treatment alternatives for patients with OSA.

Methods and analysis

Databases, including PubMed, Embase, Web of Science, SciELO, LILACS, Scopus, Cochrane Register of Controlled Trials and ClinicalTrials.gov, will be used for the search. A search strategy was developed to retrieve clinical trials that have evaluated polysomnographic primary outcome (Apnoea-Hypopnoea index) and seco

SUBMITTER: Nobre ML 

PROVIDER: S-EPMC10824059 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature