The parietal cortex has a causal role in ambiguity computations in humans.

ABSTRACT: Humans often face the challenge of making decisions between ambiguous options. The level of ambiguity in decision-making has been linked to activity in the parietal cortex, but its exact computational role remains elusive. To test the hypothesis that the parietal cortex plays a causal role in computing ambiguous probabilities, we conducted consecutive fMRI and TMS-EEG studies. We found that participants assigned unknown probabilities to objective probabilities, elevating the uncertainty of their decisions. Parietal cortex activity correlated with the objective degree of ambiguity and with a process that underestimates the uncertainty during decision-making. Conversely, the midcingulate cortex (MCC) encodes prediction errors and increases its connectivity with the parietal cortex during out

SUBMITTER: Valdebenito-Oyarzo G 

PROVIDER: S-EPMC10824459 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature