Racial and ethnic diversity in global neuroscience clinical trials.

ABSTRACT:

Background

Despite efforts to increase diversity in neuroscience trials, racial and ethnic minority groups remain underrepresented. Disparities in clinical trial participation could reflect unequal opportunities to participate and may contribute to decreased generalizability of findings and failure to identify important differences in efficacy and safety outcomes.

Methods

We retrospectively reviewed the F. Hoffmann-La Roche database for global, multicenter, neuroscience clinical trials from February 2016 to February 2021 and summarized and stratified race and ethnicity distributions by clinical trial therapeutic area and by country. These data were then compared to national population data for each study's targeted age group (available for studies conducted in the US, Canada

SUBMITTER: Rutten-Jacobs L 

PROVIDER: S-EPMC10824686 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature