Clinical and microbiological predictors of healing in Buruli ulcer disease.

ABSTRACT:

Introduction

Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting the time to healing can help improve the management of Buruli ulcer. We examine three methods for the determination of RoH and their use as predictors of time to healing.

Methods

Lesion measurements of Buruli ulcer patients treated from 2007 to 2022 were obtained with acetate sheet tracings (2D) or Aranz software (3D) fortnightly. RoH was determined using the absolute area, percentage area reduction and linear methods at 4 weeks post onset of antibiotic treatment. Predicted time to healing was compared to the actual healing time. Baseline characteristics were assessed for associations with healing.

Results

All three methods for calculating t

SUBMITTER: Agbavor B 

PROVIDER: S-EPMC10825362 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature