The need for pre-emptive control strategies for mpox in Asia and Oceania.

ABSTRACT:

Introduction

The transmission dynamics of the recent mpox outbreak highlights the lack of infrastructure available to rapidly respond to novel STI outbreaks, of which Asia and Oceania remains particularly susceptible. Here, we simulate outbreaks in this setting and propose the use of pre-emptive vaccination within the men who have sex with men (MSM) community before the arrival and establishment of the virus.

Materials and methods

Using data driven heterogeneous sexual contact networks, we simulated outbreaks of mpox in Singapore, Hong Kong, and Sydney. An individual based SEIR compartmental model was used to simulate epidemic trajectories and the impact of different vaccination uptakes was assessed in their ability to avert or suppress outbreaks upon the arrival of mpox wit

SUBMITTER: Gan G 

PROVIDER: S-EPMC10825486 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature