Demonstrating the Analytical Potential of a Wearable Microneedle-Based Device for Intradermal CO₂ Detection.

ABSTRACT: Monitoring of carbon dioxide (CO₂) body levels is crucial under several clinical conditions (e.g., human intensive care and acid-base disorders). To date, painful and risky arterial blood punctures have been performed to obtain discrete CO₂ measurements needed in clinical setups. Although noninvasive alternatives have been proposed to assess CO₂, these are currently limited to benchtop devices, requiring trained personnel, being tedious, and providing punctual information, among other disadvantages. To the best of our knowledge, the literature and market lack a wearable device for real-time, on-body monitoring of CO₂. Accordingly, we have developed a microneedle (MN)-based sensor array, labeled as CO₂-MN, comprising a combination of po

SUBMITTER: Molinero-Fernandez A 

PROVIDER: S-EPMC10825866 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature