Thromboembolic and bleeding events after valvular intervention in patients with atrial fibrillation.

ABSTRACT:

Aim

To assess outcomes after cardiac surgery with biological valve replacement, valve repair or transcatheter aortic valve implantation (TAVI) in patients with atrial fibrillation (AF) in accordance with oral anticoagulant (OAC) treatment.

Methods

All patients in Sweden undergoing valvular intervention with AF were included. Associations between OAC exposure and cardiovascular (CV) events (composite of CV death, ischaemic stroke or systemic embolism) and major bleeding were investigated using Cox regression analysis. The analysis was separated in time periods of 0-3 and 3-12 months after discharge.

Results

4730 patients were included in the first time period, 54.0% had received a surgical biological valve prosthesis, 23.8% valve repair and 22.2% TAVI. Exposure to warf

SUBMITTER: Skogseid EL 

PROVIDER: S-EPMC10826562 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature