Multicenter Retrospective Study of Invasive Fusariosis in Intensive Care Units, France.

ABSTRACT: Invasive fusariosis can be life-threatening, especially in immunocompromised patients who require intensive care unit (ICU) admission. We conducted a multicenter retrospective study to describe clinical and biologic characteristics, patient outcomes, and factors associated with death and response to antifungal therapy. We identified 55 patients with invasive fusariosis from 16 ICUs in France during 2002----2020. The mortality rate was high (56%). Fusariosis-related pneumonia occurred in 76% of patients, often leading to acute respiratory failure. Factors associated with death included elevated sequential organ failure assessment score at ICU admission or history of allogeneic hematopoietic stem cell transplantation or hematologic malignancies. Neither voriconazole treatment nor disseminate

SUBMITTER: Demonchy J 

PROVIDER: S-EPMC10826781 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature