A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data.

ABSTRACT: Stroke, a major global health concern often rooted in cardiac dynamics, demands precise risk evaluation for targeted intervention. Current risk models, like the CHA₂DS₂-VASc score, often lack the granularity required for personalized predictions. In this study, we present a nuanced and thorough stroke risk assessment by integrating functional insights from cardiac magnetic resonance (CMR) with patient-specific computational fluid dynamics (CFD) simulations. Our cohort, evenly split between control and stroke groups, comprises eight patients. Utilizing CINE CMR, we compute kinematic features, revealing smaller left atrial volumes for stroke patients. The incorporation of patient-specific atrial displacement into our hemodynamic simulations unveils the influence of atri

SUBMITTER: Zingaro A 

PROVIDER: S-EPMC10827064 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature