Beyond Hypertension: Examining Variable Blood Pressure's Role in Cognition and Brain Structure.

ABSTRACT:

Importance

Hypertension is a known risk factor for cognitive decline and structural brain changes in aging and dementia. In addition to high blood pressure (BP), individuals may also experience variable BP, meaning that their BP fluctuates between normal and high. It is currently unclear what the effects of variable BP are on cognition and brain structure.

Objective

To investigate the influence of BP on cognition and brain structure in older adults.

Design setting and participants

This longitudinal cohort study included data from the Rush Alzheimer's Disease Center Research Resource Sharing Hub (RUSH) and the Alzheimer's Disease Neuroimaging Initiative (ADNI). Participants from the two studies were included if they had BP measurements and either cognitive scores or MR

SUBMITTER: Morrison C 

PROVIDER: S-EPMC10827268 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature