Application of validated mapping algorithms between generic PedsQL scores and utility values to individuals with sickle cell disease.

ABSTRACT:

Purpose

There is a paucity of empirically estimated health state utility (HSU) values to estimate health-related quality of life among individuals with sickle cell disease (SCD). This study aims to map the Pediatric Quality of Life Inventory generic core scales (PedsQL GCS) to HSUs for children and adolescents with SCD in the United States, using published algorithms, and to assess the construct validity of these HSUs against SCD-specific PedsQL scores.

Methods

We used the published mapping algorithms identified in four published articles, in which the PedsQL GCS was mapped to either the EuroQol-5 Dimension 3-Level, Youth Version or the Child Health Utility 9-Dimension to obtain HSUs. We employed the algorithms to calculate HSUs for a sample of children and adolescents from

SUBMITTER: Jiao B 

PROVIDER: S-EPMC10827278 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature