A proposed approach to defining per- and polyfluoroalkyl substances (PFAS) based on molecular structure and formula.

ABSTRACT: Various groups and researchers, including the authors of this work, have proposed different definitions of what constitutes per- and polyfluoroalkyl substances (PFAS). The different definitions are all based on a structural definition. Although a structural definition is reasonable, such an approach is difficult to execute if the intent is to narrow or refine the definition. This approach can also lead to inexplicable demarcations of what are and what are not PFAS. Our objective was to create a narrow, simple PFAS definition that allows interested groups to communicate with a common understanding and will also serve as a starting point to focus on substances that are of real environmental concern. Our studies have demonstrated that numerous highly fluorinated complex structures exist that

SUBMITTER: Gaines LGT 

PROVIDER: S-EPMC10827356 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature