Association between early postoperative hypoalbuminaemia and outcome after orthotopic heart transplantation.

ABSTRACT:

Objectives

In patients undergoing heart transplantation (HTX), preoperative liver impairment and consecutive hypoalbuminaemia are associated with increased mortality. The role of early postoperative hypoalbuminaemia after HTX is unclear. This study investigated the association between early postoperative hypoalbuminaemia and 1-year mortality as well as 'days alive and out of hospital' (DAOH) after HTX.

Methods

This retrospective cohort study included patients who underwent HTX at the University Hospital Duesseldorf, Germany, between 2010 and 2022. The main exposure was serum albumin concentration at intensive care unit (ICU) arrival. The primary endpoints were mortality and DAOH within 1 year after surgery. Receiver operating characteristic (ROC) curve analysis was performed

SUBMITTER: M'Pembele R 

PROVIDER: S-EPMC10827358 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature