Hyoid bone morphology in patients with isolated robin sequence - A case-control study utilizing 3D morphable models.

ABSTRACT:

Background

Abnormalities of the hyoid bone are associated with impairment of oropharyngeal functions including feeding, swallowing, and breathing. Few studies have characterized anatomic abnormalities of the hyoid in patients with Robin sequence (RS), e.g. a less mineralized and voluminous hyoid. The purpose of this study was to compare normal hyoid bone morphology and hyoid bone morphology in children with isolated RS.

Methods

Three-dimensional (3D) reconstructions of the hyoid bone were obtained from CT-imaging of children with RS and unaffected controls. A 3D morphable model was constructed using Principal Component Analysis (PCA). Partial least squares - Discriminant Analysis (PLS-DA) and multivariate analysis of variance (MANOVA) were used to characterize and compare hy

SUBMITTER: Van Den Berg CPOM 

PROVIDER: S-EPMC10827493 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature