Superior rat wound-healing activity of green synthesized silver nanoparticles from acetonitrile extract of <i>Juglans regia</i> L: Pellicle and leaves.

ABSTRACT: The process of wound healing is complicated. Antimicrobial silver has been one of the substances used for wounds since ancient times. Moreover, traditional medicine has long used Juglans regia L. to promote wound healing. Since eco-friendly nanotechnology has various uses in biomedical research, the aim of this study was to assess the wound-healing capacity of bio-reduced silver nanoparticles (AgNPs). UV, DLS, TEM, and FTIR were used to characterize the prepared AgNPs. Pellicle's bioreduced AgNP (AgNP/P) has a better polydispersity index (PI) of 0.336 compared to its chemically synthesized peers, which have a PI of 0.67. Using incision and excision wound healing models, AgNPs and extracts were compared to Solcoseryl®. Skin-breaking strength, wound contraction, epithelialization time

SUBMITTER: Al-Nadaf AH 

PROVIDER: S-EPMC10827513 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature