Characterizing the Extracellular Matrix Transcriptome of Endometriosis.

ABSTRACT: In recent years, the matrisome, a set of proteins that make up the extracellular matrix (ECM) or are closely involved in ECM behavior, has been shown to have great importance for characterizing and understanding disease pathogenesis and progression. The matrisome is especially critical for examining diseases characterized by extensive tissue remodeling. Endometriosis is characterized by the extrauterine growth of endometrial tissue, making it an ideal condition to study through the lens of matrisome gene expression. While large gene expression datasets have become more available and gene dysregulation in endometriosis has been the target of several studies, the gene expression profile of the matrisome specifically in endometriosis has not been well characterized. In our study, we explored

SUBMITTER: Cook CJ 

PROVIDER: S-EPMC10827821 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature