Yield of non-invasive imaging in MRI-negative focal epilepsy.

ABSTRACT:

Objective

The absence of MRI-lesion reduces considerably the probability of having an excellent outcome (International League Against Epilepsies [ILAE] class I-II) after epilepsy surgery. Surgical success in magnetic-resonance imaging (MRI)-negative cases relies therefore mainly on non-invasive techniques such as positron-emission tomography (PET), subtraction ictal/inter-ictal single-photon-emission-computed-tomography co-registered to MRI (SISCOM), electric source imaging (ESI) and morphometric MRI analysis (MAP). We were interested in identifying the optimal imaging technique or combination to achieve post-operative class I-II in patients with MRI-negative focal epilepsy.

Methods

We identified 168 epileptic patients without MRI lesion. Thirty-three (19.6%) were diagnosed

SUBMITTER: Czarnetzki C 

PROVIDER: S-EPMC10827933 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature