Pyrosequencing analysis of bacterial community changes in dental unit waterlines after chlorogenic acid treatment.

ABSTRACT:

Introduction

The contamination of dental unit waterlines (DUWLs) poses a significant risk of cross-infection in dentistry. Although chemical disinfectants have been effective in reducing number of bacteria, they do have limitations.

Methods

This study aimed to investigate the potential of chlorogenic acid, a natural substance with broadspectrum antibacterial properties, for treating DUWLs. Over a period of three months, we analyzed the microbial communities in 149 DUWLs samples collected from 5 dental units using high-throughput pyrophosphate sequencing.

Results

The results revealed that chlorogenic acid treatment had a significant impact on the microbial community profile in the DUWLs, with the most significant changes occurring within the first 15 days and stabiliza

SUBMITTER: Li N 

PROVIDER: S-EPMC10828043 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature