Global Prevalence of Varicella-Associated Complications: A Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Varicella (chickenpox) is an infectious disease caused by the varicella zoster virus affecting children, adolescents, and adults. Varicella symptoms are usually self-limiting; however, different complications with widespread and systemic manifestations can occur. This systematic literature review aims to explore and quantify varicella-associated complication rates.

Methods

Two databases (Embase and MEDLINE), congress abstracts, and reference lists of systematic reviews were screened to identify evidence on varicella complications. Complications were identified and grouped into 14 clinically relevant categories. Proportional meta-analyses were conducted using a random-effects model and tests for heterogeneity and publication bias were performed. Subgroup, sensiti

SUBMITTER: Shah HA 

PROVIDER: S-EPMC10828225 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature