Beyond the aging spine - a systematic review of functional changes in the human brain in cervical spondylotic myelopathy.

ABSTRACT: Cervical Spondylotic Myelopathy (CSM) is a degenerative condition that leads to loss of cervical spinal cord integrity, typically affecting the aged population. Emerging fMRI-based evidence suggests that the brain is also affected by CSM. This systematic review aimed to understand the usefulness of brain fMRI in CSM. A comprehensive literature search was conducted until March 2023 according to PRISMA guidelines. The inclusion criteria included original research articles in English, primarily studying the human brain's functional changes in CSM using fMRI with at least 5 participants. The extracted data from each study included demographics, disease severity, MRI machine characteristics, affected brain areas, functional changes, and clinical utilities. A total of 30 studies met the inclusio

SUBMITTER: Khan AF 

PROVIDER: S-EPMC10828266 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature