Associations of healthy aging index and all-cause and cause-specific mortality: a prospective cohort study of UK Biobank participants.

ABSTRACT: The healthy aging index (HAI) has been recently developed as a surrogate measure of biological age. However, to what extent the HAI is associated with all-cause and cause-specific mortality and whether this association differs in younger and older adults remains unknown. We aimed to quantify the association between the HAI and mortality in a population of UK adults. In the prospective cohort study, data are obtained from the UK Biobank. Five HAI components (systolic blood pressure, reaction time, cystatin C, serum glucose, forced vital capacity) were scored 0 (healthiest), 1, and 2 (unhealthiest) according to sex-specific tertiles or clinically relevant cut-points and summed to construct the HAI (range 0-10). Cox proportional hazard regression models were used to estimate the associations

SUBMITTER: Zhuang Z 

PROVIDER: S-EPMC10828282 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature