A systematic review and meta-analysis of the effects of physical exercise on white matter integrity and cognitive function in older adults.

ABSTRACT: In the context of a globally aging population, exploring interventions that counteract age-related cognitive decline and cerebral structural alterations is paramount. Among various strategies, physical exercise (PE) emerges as a prevalent activity routinely incorporated in many individuals' lives. This systematic review and meta-analysis aims to elucidate the impact of PE on white matter (WM) integrity and cognitive function in older adults. Data from 581 participants, 312 in the PE intervention group, and 269 in the control group were extracted from nine randomized controlled trials (RCTs) retrieved from databases including PubMed, Embase, Web of Science, and the Cochrane Library. The results indicated a significant improvement in white matter (WM) integrity in individuals engaged in PE,

SUBMITTER: Zhang W 

PROVIDER: S-EPMC10828294 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature