The microarchitecture and chemical composition of the femur neck of senescent female rats after different physical training protocols.

ABSTRACT: A sedentary lifestyle, coupled with a decrease in estrogen, impairs bone homeostasis, favoring to the development of osteopenia and osteoporosis, both recognized as risk factors for fractures. Here, we investigated the quality of the femur, particularly the femur neck region, and the ambulation performance of senescent rats subjected to three different physical training protocols during the periestropause period. Forty-eight female rats, 18 months of age, were subjected to a 120-day training period, three times a week. The rats were distributed into four groups: aerobic training (AT), strength training (ST), concurrent training (CT), or no training (NT). After the experimental period, at 21 months of age, ambulation performance and femur were analyzed using microtomography, Raman stereolog

SUBMITTER: Dos Santos Silva RA 

PROVIDER: S-EPMC10828330 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature