IProPhos: A Web-Based Interactive Platform for Integrated Proteome and Phosphoproteome Analysis.

ABSTRACT: Large-scale omics studies have generated a wealth of mass spectrometry-based proteomics data, which provide additional insights into disease biology spanning genomic boundaries. However, there is a notable lack of web-based analysis and visualization tools that facilitate the reutilization of these data. Given this challenge, we present iProPhos, a user-friendly web server to deliver interactive and customizable functionalities. iProPhos incorporates a large number of samples, including 1444 tumor samples and 746 normal samples across 12 cancer types, sourced from the Clinical Proteomic Tumor Analysis Consortium. Additionally, users can also upload their own proteomics/phosphoproteomics data for analysis and visualization. In iProPhos, users can perform profiling plotting and differential

SUBMITTER: Zou J 

PROVIDER: S-EPMC10828474 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature