Mitomycin intravascular chemoembolization (MICE) to treat corneal vascularization prior to penetrating keratoplasty.

ABSTRACT:

Purpose

To present the clinical outcome of mitomycin intravascular chemoembolization (MICE) as a prophylactic treatment in a patient with HSV-induced corneal neovascularization (NV) before penetrating keratoplasty (PKP).

Observations

A 53-year-old male patient presented with a medical history of recurrent herpes simplex virus (HSV) corneal infection. The patient reported worsening visual acuity despite maintenance treatment with systemic antivirals and topical corticosteroids. After the appearance of corneal NV, subconjunctival triamcinolone and bevacizumab injections were given with limited and temporary improvement. Due to worsening corneal NV, MICE was subsequently performed, resulting in the elimination of corneal NV from the visual axis, which allowed for successful PKP

SUBMITTER: Rangu N 

PROVIDER: S-EPMC10828578 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature