White matter hyperintensities in diverse populations: A systematic review of literature in the United States.

ABSTRACT: As the United States' (US) elderly population becomes increasingly diverse, it is imperative that research studies address cognitive health in diverse populations of older Americans. White Matter Hyperintensities (WMH) are useful imaging findings that can be studied in elderly individuals and have been linked to an increased risk of neurological conditions, such as stroke, cognitive impairment, and dementia. We performed a systematic review of literature using PubMed sources to compile all the studies that investigated the prevalence of ethnic and racial differences of WMH burden amongst diverse groups in the US. We identified 23 unique articles that utilized 16 distinct cohorts of which 94 % were prospective, longitudinal studies that included community-based and family-based populations.

SUBMITTER: Farkhondeh V 

PROVIDER: S-EPMC10828602 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature