Genetic outcomes in children with developmental language disorder: a systematic review.

ABSTRACT:

Introduction

Developmental language disorder (DLD) is a common childhood condition negatively influencing communication and psychosocial development. An increasing number of pathogenic variants or chromosomal anomalies possibly related to DLD have been identified. To provide a base for accurate clinical genetic diagnostic work-up for DLD patients, understanding the specific genetic background is crucial. This study aims to give a systematic literature overview of pathogenic variants or chromosomal anomalies causative for DLD in children.

Methods

We conducted a systematic search in PubMed and Embase on available literature related to the genetic background of diagnosed DLD in children. Included papers were critically appraised before data extraction. An additional search in O

SUBMITTER: van Wijngaarden V 

PROVIDER: S-EPMC10828955 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature