Study of Herbs Cortex Moutan, Poria cocos, and Alisma orientale and Periodontitis.

ABSTRACT:

Introduction

The Chinese traditional herbs Cortex Moutan, Poria cocos, and Alisma orientale are considered to have potential to ameliorate periodontitis, although the possible underlying mechanisms remain mostly unknown. Due to the complex formulation of Chinese herbs, it is important to understand the mechanisms of pharmacologic effects of traditional herbs for better application in modern medical treatment.

Methods

Network pharmacology was applied to explore the mechanism of Cortex Moutan, Poria cocos, and Alisma orientale. First we analysed their chemical ingredients using the Traditional Chinese Medicine Systems Pharmacology database and identified 20 active ingredients. Then we analysed the target genes of these 20 active ingredients as well as genes associated with per

SUBMITTER: Hu X 

PROVIDER: S-EPMC10829340 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature