Dexmedetomidine versus midazolam as intranasal premedication for intravenous deep sedation in pediatric dental treatment.

ABSTRACT:

Background/purpose

Optimal sedation management for pediatric dental treatment demands special focus as it's tubeless and shares a same oral space. The study was to evaluate dexmedetomidine compared to midazolam for intranasal premedication in pediatric dental treatment under intravenous deep sedation.

Materials and methods

A hundred children aged 3-7 years scheduled for elective dental treatment under intravenous deep sedation anesthesia were enrolled, of whom 50 children (Group D) were intranasally premedicated with 2.0 μg/kg dexmedetomidine and the remaining 50 children (Group M) received traditional 0.2 mg/kg midazolam. Acceptance rate of venipuncture was regarded as the primary endpoint.

Results

The acceptance rate of venipuncture in Group D and Group M were 76% v

SUBMITTER: Cheng T 

PROVIDER: S-EPMC10829544 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature