A scientometric study of chemical carcinogen-induced experimental oral carcinogenesis with emphasis on chemopreventive agents.

ABSTRACT:

Background/purpose

4-Nitroquinoline 1-oxide (4NQO)-induced tongue carcinoma and 7,12-dimethlybenz(a)anthracene (DMBA)-induced cheek pouch carcinoma are the most common and classical chemical carcinogen-induced animal models of oral carcinogenesis. The purpose of this study was to provide the research trends and characteristics of 4NQO- and DMBA-induced experimental oral carcinogenesis.

Materials and methods

The papers on both 4NQO- and DMBA-induced experimental oral carcinogenesis were published since 1962. All the eligible papers were retrieved on 12 May 2023 from the Scopus database.

Results

There were 506 and 349 papers on 4NQO- and DMBA-induced experimental oral carcinogenesis with 10,152 and 6306 citations, respectively. The common distinctive keywords such as ra

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC10829645 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature