Oral microbiota, co-evolution, and implications for health and disease: The case of indigenous peoples.

ABSTRACT: Evidence indicates that oral microbiota plays a crucial role in human health and disease. For instance, diseases with multifactorial etiology, such as periodontitis and caries, which cause a detrimental impact on human well-being and health, can be caused by alterations in the host-microbiota interactions, where non-pathogenic bacteria give way to pathogenic orange/red-complex bacterial species (a change from a eubiotic to dysbiotic state). In this scenario, where thousands of oral microorganisms, including fungi, archaea, and phage species, and their host are co-evolving, a set of phenomena, such as the arms race and Red or Black Queen dynamics, are expected to operate. We review concepts on the subject and revisit the nature of bacterial complexes linked to oral health and diseases, as w

SUBMITTER: Marcano-Ruiz M 

PROVIDER: S-EPMC10829892 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature