Point-of-Care Coating of Revision Femoral Stems With Antibiotic-Loaded Calcium Sulfate: Reduction in Infection After 2nd Stage Reimplantation but Not With Aseptic Revisions.

ABSTRACT:

Background

Infection rates in revision total hip arthroplasty are lower when antibiotic loaded cemented stems are utilized. Inspired by this technique, a point-of-care coating of antibiotic-loaded calcium sulfate (CaSO₄) was applied to cementless revision stems in aseptic revision and 2nd stage reimplantation total hip arthroplasty.

Methods

One hundred eleven consecutive femoral stems were coated. Just prior to insertion, 10 cc of CaSO₄ was mixed with 1 g vancomycin and 240 mg tobramycin with the paste applied to the stem. The results were compared to a matched cohort (N = 104) performed across the previous 5 years. The surgical methods were comparable, but for the stem coating. The study group was followed for a minimum of 3 years.

Results

In th

SUBMITTER: McPherson EJ 

PROVIDER: S-EPMC10830497 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature