Identification and molecular analysis of lbpBA, which encodes the two-component meningococcal lactoferrin receptor.

ABSTRACT: We identified lbpB, encoding the lipoprotein component of the meningococcal lactoferrin receptor. An LbpB mutant was unable to acquire Fe from lactoferrin and exhibits decreased surface binding to lactoferrin. Primer extension and reverse transcription-PCR analysis indicate that lbpB and lbpA are cotranscribed on a polycistronic Fe-repressible mRNA.

SUBMITTER: Lewis LA 

PROVIDER: S-EPMC108307 | biostudies-literature | 1998 Jun

REPOSITORIES: biostudies-literature