Optimal assessment of the glomerular filtration rate in older chinese patients using the equations of the Berlin Initiative Study.

ABSTRACT:

Aim

To evaluate the performances of the various estimated glomerular filtration rate (eGFR) equations of the Chronic Kidney Disease Epidemiology Collaboration, the Berlin Initiative Study (BIS), and the Full Age Spectrum (FAS) in older Chinese.

Methods

This study enrolled Chinese adults aged ≥ 65 years who underwent GFR measurements (via 99Tcm-DTPA renal dynamic imaging) in our hospital from 2011 to 2022. Using the measured glomerular filtration rate (mGFR) as the reference, we derived the bias, precision, accuracy, and consistency of each equation.

Results

We enrolled 519 participants, comprising 155 with mGFR ≥ 60 mL/min/1.73 m² and 364 with mGFR < 60 mL/min/1.73 m². In the total patients, the BIS equation based on creatinine and cystatin C (BI

SUBMITTER: Yang Y 

PROVIDER: S-EPMC10830815 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature