Prognostic Value of ¹⁸F-FDG PET/CT Radiomics in Extranodal Nasal-Type NK/T Cell Lymphoma.

ABSTRACT:

Objective

To investigate the prognostic utility of radiomics features extracted from ¹⁸F-fluorodeoxyglucose (FDG) PET/CT combined with clinical factors and metabolic parameters in predicting progression-free survival (PFS) and overall survival (OS) in individuals diagnosed with extranodal nasal-type NK/T cell lymphoma (ENKTCL).

Materials and methods

A total of 126 adults with ENKTCL who underwent ¹⁸F-FDG PET/CT examination before treatment were retrospectively included and randomly divided into training (n = 88) and validation cohorts (n = 38) at a ratio of 7:3. Least absolute shrinkage and selection operation Cox regression analysis was used to select the best radiomics features and calculate each patient's radiomics scores (RadPFS and RadOS). Kaplan-M

SUBMITTER: Luo Y 

PROVIDER: S-EPMC10831304 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature