Timing to First Whole Blood Transfusion and Survival Following Severe Hemorrhage in Trauma Patients.

ABSTRACT:

Importance

Civilian trauma centers have revived interest in whole-blood (WB) resuscitation for patients with life-threatening bleeding. However, there remains insufficient evidence that the timing of WB transfusion when given as an adjunct to a massive transfusion protocol (MTP) is associated with a difference in patient survival outcome.

Objective

To evaluate whether earlier timing of first WB transfusion is associated with improved survival at 24 hours and 30 days for adult trauma patients presenting with severe hemorrhage.

Design, setting, and participants

This retrospective cohort study used the American College of Surgeons Trauma Quality Improvement Program databank from January 1, 2019, to December 31, 2020, for adult patients presenting to US and Canadian adult

SUBMITTER: Torres CM 

PROVIDER: S-EPMC10831629 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature