Associations of severe liver diseases with cataract using data from UK Biobank: a prospective cohort study.

ABSTRACT:

Background

Liver disease is linked to series of extrahepatic multisystem manifestations. However, little is known about the associations between liver and eye diseases, especially cataract, the global leading cause of blindness. We aimed to investigate whether severe liver diseases, including non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD), viral hepatitis, and liver fibrosis and cirrhosis, were associated with an increased risk of the cataract.

Methods

A total of 326,558 participants without cataract at baseline enrolled in the UK Biobank between 2006 and 2010 were included in this prospective study. The exposures of interest were severe liver diseases (defined as hospital admission), including NAFLD, ALD, viral hepatitis and liver fibrosis and cirr

SUBMITTER: Chen C 

PROVIDER: S-EPMC10831806 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature