Adiponectin blood levels and autism spectrum disorders: a systematic review.

ABSTRACT:

Objective

To review the relationship between adiponectin levels and autism spectrum disorders (ASDs) in children.

Background

ASDs are associated with pervasive social interaction and communication abnormalities. Researchers have studied various pathophysiological mechanisms underlying ASDs to identify predictors for an early diagnosis to optimize treatment outcomes. Immune dysfunction, perhaps mediated by a decrease in anti-inflammatory adipokine, adiponectin, along with changes in other adipokines, may play a central role in increasing the risk for ASDs. However, other factors, such as low maternal vitamin D levels, atherosclerosis, diabetes, obesity, cardio-metabolic diseases, preterm delivery, and oxytocin gene polymorphism may also contribute to increased risk for ASDs.<

SUBMITTER: Ali M 

PROVIDER: S-EPMC10832114 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature