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Remifentanil improves left ventricular diastolic parameters in patients with impaired diastolic function: a prospective clinical study.


ABSTRACT:

Background

Left ventricular diastolic dysfunction has a significant impact on perioperative morbidity and mortality, and its incidence is high in elderly individuals. Anesthetic agents may impair diastolic function, which may increase the incidence of perioperative complications. The aim of this prospective, clinical, phase 4 study was to investigate the effects of remifentanil on left ventricle (LV) diastolic function in patients with diastolic dysfunction. The study was performed on 30 spontaneously breathing subjects (aged 60-80 years) with diastolic dysfunction.

Methods

Thirty patients (aged 60-80 years) with diastolic dysfunction scheduled for surgery were recruited between November 2019 and March 2023. Left ventricle function was evaluated once the intravenous remifent

SUBMITTER: Koner O 

PROVIDER: S-EPMC10832159 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature