Kdr mutations and deltamethrin resistance in house flies in Abu Dhabi, UAE.

ABSTRACT:

Background

The house fly, Musca domestica, is a significant carrier of diseases that can impact public health. Repeated use of pyrethroid insecticides may act as a selection pressure for mutations and amino acid substitutions in the house fly voltage-sensitive sodium channel (VSSC), which ultimately confers resistance. The objectives of this study were to determine the presence of knockdown resistance (kdr) mutations using molecular tools and to set up a CDC bottle bioassay specific for house flies in the United Arab Emirates (UAE) to screen for deltamethrin resistance.

Methods

Adult flies were collected from 19 locations in Abu Dhabi, UAE, and DNA was extracted, followed by PCR amplification of specific alleles (PASA) and conventional PCR using several primers to amplify re

SUBMITTER: Hamdan M 

PROVIDER: S-EPMC10832251 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature